The city of Sioux Falls, South Dakota, currently has 3 active clinical trials seeking participants for Type 1 Diabetes research studies.
Type 1 Diabetes Extension Study
Recruiting
This is a multi-center, prospective, non-interventional study that focuses on the long- term effects following participation in selected ITN new-onset Type1 Diabetes Mellitus studies with immunomodulatory agents (T1DM, T1D). This observational study will: * follow participants to determine how long they continue to produce insulin, and * will also assess how changes in the immune system over time relate to the ability to produce insulin. This information could help design better therapies for... Read More
Gender:
ALL
Ages:
Between 8 years and 35 years
Trial Updated:
04/09/2025
Locations: Sanford Research, Sioux Falls, South Dakota
Conditions: Type 1 Diabetes Mellitus, T1DM, T1D
Rituximab-pvvr and Abatacept Vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes
Recruiting
The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to a 2-hour mixed meal tolerance test, will be improved in participants with new onset T1D who are treated with Abatacept after Rituximab-pvvr compared to those treated with Rituximab-pvvr and placebo 24 months after enrollment.
Gender:
ALL
Ages:
Between 8 years and 45 years
Trial Updated:
09/27/2024
Locations: Sanford Children's Specialty Clinic, Sioux Falls, South Dakota
Conditions: Type 1 Diabetes Mellitus
General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery
Recruiting
In partnership with Helmsley Charitable Trust, the Sanford PLEDGE Study is a large-scale, observational, feasibility study of general population screening for T1D and celiac autoantibodies. Screening is incorporated into routine health care visits within an integrated health system.
Gender:
ALL
Ages:
Between 0 minutes and 17 years
Trial Updated:
04/19/2024
Locations: Sanford Sioux Falls Region Clinics, Sioux Falls, South Dakota
Conditions: Type 1 Diabetes, Celiac Disease